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4-Chloro-L-phenylalanine

4-Chloro-L-phenylalanine (L-PCPA) is a 5-HT biosynthesis inhibitor. 4-Chloro-L-phenylalanine is also a nonspecific antagonist of both isoforms of tryptophan hydroxylase (TPH1 and TPH2) [1].

Product Specifications

CAS Number

14173-39-8

Product Name Alternative

L-PCPA

UNSPSC

12352209

Hazard Statement

H301, H317

Target

5-HT Receptor; Tryptophan Hydroxylase

Type

Peptides

Related Pathways

GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/4-chloro-l-phenylalanine.html

Purity

98.19

Solubility

H2O : 10.29 mg/mL (ultrasonic)

Smiles

N[C@@H](CC1=CC=C(Cl)C=C1)C(O)=O

Molecular Formula

C9H10ClNO2

Molecular Weight

199.64

Precautions

H301, H317

References & Citations

[1]Chasen J Greig, et al. Enhanced serotonin signaling increases intestinal neuroplasticity. J Surg Res. 2016 Nov;206 (1) :151-158.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Peptides

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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