4-Chloro-L-phenylalanine
4-Chloro-L-phenylalanine (L-PCPA) is a 5-HT biosynthesis inhibitor. 4-Chloro-L-phenylalanine is also a nonspecific antagonist of both isoforms of tryptophan hydroxylase (TPH1 and TPH2) [1].
Product Specifications
CAS Number
[14173-39-8]
Product Name Alternative
L-PCPA
UNSPSC
12352209
Hazard Statement
H301, H317
Target
5-HT Receptor; Tryptophan Hydroxylase
Type
Peptides
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/4-chloro-l-phenylalanine.html
Purity
98.19
Solubility
H2O : 10.29 mg/mL (ultrasonic)
Smiles
N[C@@H](CC1=CC=C(Cl)C=C1)C(O)=O
Molecular Formula
C9H10ClNO2
Molecular Weight
199.64
Precautions
H301, H317
References & Citations
[1]Chasen J Greig, et al. Enhanced serotonin signaling increases intestinal neuroplasticity. J Surg Res. 2016 Nov;206 (1) :151-158.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
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