Recombinant human TNFSF15 protein
Product Specifications
Background
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]
Gene ID
9966
Swiss Prot
O95150
Expression System
E.coli
Conjugation
Unconjugated
Tag
N-His
Source
Recombinant human TNFSF15 protein is expressed in E.coliwith N-His. It contains the amino acid sequence of 72-251/251
Applications
Others
Endotoxin
Not Tested
Purity
> 90% as determined by SDS- PAGE
Buffer
20mM Tris-Hcl (pH=8.0) with 8M Urea
Storage Conditions
The product should be stored at -70°C or -20°C.
Species
Others
Gene ID URL
9966
Available Sizes
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