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Recombinant human HIF-1 Alpha protein, N-Trx-His

Product Specifications

Background

Hypoxia-inducible factor-1 (HIF1) is a transcription factor found in mammalian cells cultured under reduced oxygen tension that plays an essential role in cellular and systemic homeostatic responses to hypoxia. HIF1 is a heterodimer composed of an alpha subunit and a beta subunit. The beta subunit has been identified as the aryl hydrocarbon receptor nuclear translocator (ARNT) . This gene encodes the alpha subunit of HIF-1. Overexpression of a natural antisense transcript (aHIF) of this gene has been shown to be associated with nonpapillary renal carcinomas. Two alternative transcripts encoding different isoforms have been identified.

Gene ID

3091

Swiss Prot

Q16665

Expression System

E.coli

Conjugation

Unconjugated

Tag

N-Trx-His

Source

Recombinant human HIF-1 Alpha protein is expressed in E.coli with N-Trx-His. It contains the amino acid sequence of 575-826/826

Applications

Others

Endotoxin

Not Tested

Purity

> 90% as determined by SDS- PAGE

Buffer

0.01M TBS (pH7.4)

Storage Conditions

The product should be stored at -70°C or -20°C.

Species

Others

Gene ID URL

3091

Available Sizes

Curated Selection

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