Recombinant human CXCR3 protein, N-Trx&His
Product Specifications
Background
This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant) . Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716) . [provided by RefSeq, Jun 2011].
Gene ID
2833
Swiss Prot
P49682
Expression System
E.coli
Conjugation
Unconjugated
Tag
N-Trx-His
Source
Recombinant human CXCR3 protein is expressed in E.coli with N-Trx-His. It contains the amino acid sequence of 1-53/368
Applications
Others
Endotoxin
Not Tested
Purity
> 90% as determined by SDS- PAGE
Buffer
0.01M TBS (pH7.4)
Storage Conditions
The product should be stored at -70°C or -20°C.
Species
Others
Gene ID URL
2833
Available Sizes
Frequently Asked Questions
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