Recombinant mouse NALP3 protein, N-Trx-His, APC Conjugated
Product Specifications
Background
May function as an inducer of apoptosis. Interacts selectively with ASC and this complex may function as an upstream activator of NF-kappa-B signaling. Inhibits TNF-alpha induced activation and nuclear translocation of RELA/NF-KB p65. Also inhibits transcriptional activity of RELA. Activates caspase-1 in response to a number of triggers including bacterial or viral infection which leads to processing and release of IL1B and IL18. Subcellular Location : Cytoplasm.
Gene ID
216799
Swiss Prot
Q8R4B8
Expression System
E.coli
Conjugation
APC
Tag
N-Trx-His
Source
Recombinant mouse NALP3 protein is expressed in E.coli with N-Trx-His. It contains the amino acid sequence of 1-93/1033
Applications
Others
Endotoxin
Not Tested
Purity
> 90% as determined by SDS- PAGE
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Species
Others
Gene ID URL
216799
Available Sizes
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