Recombinant mouse NALP3 protein, N-Trx-His, Biotin Conjugated
Product Specifications
Background
May function as an inducer of apoptosis. Interacts selectively with ASC and this complex may function as an upstream activator of NF-kappa-B signaling. Inhibits TNF-alpha induced activation and nuclear translocation of RELA/NF-KB p65. Also inhibits transcriptional activity of RELA. Activates caspase-1 in response to a number of triggers including bacterial or viral infection which leads to processing and release of IL1B and IL18. Subcellular Location : Cytoplasm.
Gene ID
216799
Swiss Prot
Q8R4B8
Expression System
E.coli
Conjugation
Biotin
Tag
N-Trx-His
Source
Recombinant mouse NALP3 protein is expressed in E.coli with N-Trx-His. It contains the amino acid sequence of 1-93/1033
Applications
Others
Endotoxin
Not Tested
Purity
> 90% as determined by SDS- PAGE
Buffer
Lyophilized from 0.22um filtered solution in 20mM PB (pH 7.4) . 5% trehalose is added as a protectant before lyophilization.
Storage Conditions
The product should be stored at -70°C or -20°C.
Species
Others
Gene ID URL
216799
Available Sizes
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