Recombinant human FOLR2 protein, N-His
Product Specifications
Background
The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Gene ID
2350
Swiss Prot
P14207
Expression System
E.coli
Conjugation
Unconjugated
Tag
N-His
Source
Recombinant human FOLR2 protein is expressed in E.coli with N-His. It contains the amino acid sequence of 22-228/255
Applications
Others
Endotoxin
Not Tested
Purity
> 90% as determined by SDS- PAGE
Buffer
20mM Tris-HCl (pH9.0) with 8M Urea and 5mM DTT.
Storage Conditions
The product should be stored at -70°C or -20°C.
Species
Others
Gene ID URL
2350
Available Sizes
Frequently Asked Questions
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