Recombinant human GBP2 protein, N-His
Product Specifications
Background
Guanylate-binding proteins, GBP1 and GBP2 are GTP-binding proteins with a high-turnover GTPase activity and an antiviral effect (1-4) . GBP1 mediates an antiviral effect against vesicular stomatitis virus and encephalomyocarditis virus and plays a role in the IFN-mediated antiviral response against these viruses (4) . GBP1 and GBP2 belong to a group of large GTP-binding proteins with a high concentration-dependent GTPase activity that have the common ability to undergo oligomerization (1) . GBP1 and GBP2 are bone marrow-derived GTPases encoded by interferon-activated genes and are inducible following IFN treatment (2,3) . Specifically, GBP1 is expressed in cultured mammary epithelial tumor cell lines after treatment with IFN-gamma and LPS (5) .
Gene ID
2634
Swiss Prot
P32456
Expression System
E.coli
Conjugation
Unconjugated
Tag
N-His
Source
Recombinant human GBP2 protein is expressed in E.coli with N-His. It contains the amino acid sequence of 50-306/591
Applications
Others
Endotoxin
Not Tested
Purity
> 90% as determined by SDS- PAGE
Buffer
20mM Tris (pH8.0) with 8M Urea.
Storage Conditions
The product should be stored at -70°C or -20°C.
Species
Others
Gene ID URL
2634
Available Sizes
Curated Selection
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