Recombinant human MASP2 protein, N-His
Product Specifications
Background
His gene encodes a member of the peptidase S1 family of serine proteases. The encoded preproprotein is proteolytically processed to generate A and B chains that heterodimerize to form the mature protease. This protease cleaves complement components C2 and C4 in order to generate C3 convertase in the lectin pathway of the complement system. The encoded protease also plays a role in the coagulation cascade through cleavage of prothrombin to form thrombin. Myocardial infarction and acute stroke patients exhibit reduced serum concentrations of the encoded protein. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]
Gene ID
10747
Swiss Prot
O00187
Expression System
E.coli
Conjugation
Unconjugated
Tag
N-His
Source
Recombinant human MASP2 protein is expressed in E.coli with N-His. It contains the amino acid sequence of 428-575/686
Applications
Others
Endotoxin
Not Tested
Purity
> 90% as determined by SDS- PAGE
Buffer
20mM Tris-HCl (pH8.0) with 8M Urea.
Storage Conditions
The product should be stored at -70°C or -20°C.
Species
Others
Gene ID URL
10747
Available Sizes
Curated Selection
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