4-Pentenoic acid

4-Pentenoic acid is a medium-chain unsaturated fatty acid. 4-Pentenoic acid has hypoglycemic and fatty acid oxidation inhibitory activities. 4-Pentenoic acid can affect blood glucose metabolism and energy metabolism through mechanisms such as inhibiting long-chain fatty acid oxidation, reducing gluconeogenesis, and promoting glucose utilization[1][2].

Product Specifications

CAS Number

[591-80-0]

UNSPSC

12352211

Hazard Statement

H227, H302, H314

Target

Endogenous Metabolite; Mitochondrial Metabolism

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/4-pentenoic-acid.html

Purity

99.93

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : 65 mg/mL (ultrasonic)

Smiles

C=CCCC(O)=O

Molecular Formula

C5H8O2

Molecular Weight

100.12

Precautions

H227, H302, H314

References & Citations

[1]Schulz H. Metabolism of 4-pentenoic acid and inhibition of thiolase by metabolites of 4-pentenoic acid. Biochemistry. 1983 Apr 12;22 (8) :1827-32.|[2]Corredor C, et al. Studies of the mechanism of the hypoglycemic action of 4-pentenoic acid. Proc Natl Acad Sci U S A. 1967 Dec;58 (6) :2299-306.|[3]Schulz H, et al. [48] 4-Pentenoic acid[M]//Methods in enzymology. Academic Press, 1981, 72: 604-610.