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Recombinant human GCH1 protein, C-His, Biotin Conjugated

Product Specifications

Background

GTP cyclohydrolase I (also designated dopa-responsive dystonia) catalyzes the conversion of GTP to D-erythro-7,8-dihydroneopterin triphosphate, the first and rate-limiting step in tetrahydrobiopterin (BH4) biosynthesis. Tetrahydrobiopterin is an essential cofactor for 3 aromatic amino acid monooxygenases: phenylalanine, tyrosine, and tryptophan hydroxylases. Animals can synthesize tetrahydrobiopterin in vivo from GTP through several enzymatic reactions.

Gene ID

2643

Swiss Prot

P30793

Expression System

E.coli

Conjugation

Biotin

Tag

C-His

Source

Recombinant human GCH1 protein is expressed in E.coli with C-His. It contains the amino acid sequence of 1-250/250

Applications

Others

Endotoxin

Not Tested

Purity

> 90% as determined by SDS- PAGE

Buffer

Lyophilized from 0.22um filtered solution in 20mM PB (pH 7.4) . 5% trehalose is added as a protectant before lyophilization.

Storage Conditions

The product should be stored at -70°C or -20°C.

Species

Others

Gene ID URL

2643

Available Sizes

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