Recombinant human GCH1 protein, C-His, Biotin Conjugated
Product Specifications
Background
GTP cyclohydrolase I (also designated dopa-responsive dystonia) catalyzes the conversion of GTP to D-erythro-7,8-dihydroneopterin triphosphate, the first and rate-limiting step in tetrahydrobiopterin (BH4) biosynthesis. Tetrahydrobiopterin is an essential cofactor for 3 aromatic amino acid monooxygenases: phenylalanine, tyrosine, and tryptophan hydroxylases. Animals can synthesize tetrahydrobiopterin in vivo from GTP through several enzymatic reactions.
Gene ID
2643
Swiss Prot
P30793
Expression System
E.coli
Conjugation
Biotin
Tag
C-His
Source
Recombinant human GCH1 protein is expressed in E.coli with C-His. It contains the amino acid sequence of 1-250/250
Applications
Others
Endotoxin
Not Tested
Purity
> 90% as determined by SDS- PAGE
Buffer
Lyophilized from 0.22um filtered solution in 20mM PB (pH 7.4) . 5% trehalose is added as a protectant before lyophilization.
Storage Conditions
The product should be stored at -70°C or -20°C.
Species
Others
Gene ID URL
2643
Available Sizes
Curated Selection
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