Recombinant human PALB2 protein, APC Conjugated
Product Specifications
Background
This gene encodes a protein that may function in tumor suppression. This protein binds to and colocalizes with the breast cancer 2 early onset protein (BRCA2) in nuclear foci and likely permits the stable intranuclear localization and accumulation of BRCA2. Essential partner of BRCA2 that promotes the localization and stability of BRCA2. Also enables its recombinational repair and checkpoint functions of BRCA2. May act by promoting stable association of BRCA2 with nuclear structures, allowing BRCA2 to escape the effects of proteosome-mediated degradation.
Gene ID
79728
Swiss Prot
Q86YC2
Expression System
E.coli
Conjugation
APC
Tag
His&Trx&S
Source
Recombinant human PALB2 protein is expressed in E.coli with His&Trx&S. It contains the amino acid sequence of 841-1186/1186
Applications
Others
Endotoxin
Not Tested
Purity
> 90% as determined by SDS- PAGE
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Species
Others
Gene ID URL
79728
Available Sizes
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