Recombinan human ACE2 Protein, N-His
Product Specifications
Background
Angiotensin-converting enzyme 2 (ACE2) is an enzyme attached to the outer surface (cell membranes) of cells in the lungs, arteries, heart, kidney, and intestines. ACE2 lowers blood pressure by catalyzing the hydrolysis of angiotensin II (a vasoconstrictor peptide) into angiotensin (1–7) (a vasodilator) . ACE2 counters the activity of the related angiotensin-converting enzyme (ACE) by reducing the amount of angiotensin-II and increasing Ang (1-7) making it a promising drug target for treating cardiovascular diseases. ACE2 also serves as the entry point into cells for some coronaviruses including Severe acute respiratory syndrome coronavirus 2.
Gene ID
NP_001358344.1
Expression System
E.coli
Conjugation
Unconjugated
Tag
N-His
Source
Recombinan human ACE2 Protein, N-His protein is expressed in E.coli with N-His. It contains the amino acid sequence of 18-615aa.
Applications
WB, ELISA
Endotoxin
Not Tested
Purity
>95% as determined by SDS-PAGE
Buffer
Lyophilized from 0.22um filtered solution in 20mM PB (pH 7.4) . 5% trehalose is added as a protectant before lyophilization.
Storage Conditions
The product should be stored at -70°C or -20°C.
Species
Human
Gene ID URL
NP_001358344.1
Available Sizes
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