Recombinant human Bax protein, DsbC & His
Product Specifications
Background
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq, Jul 2008].
Gene ID
581
Swiss Prot
Q07812
Expression System
E.coli
Conjugation
Unconjugated
Tag
DsbC & His
Source
Recombinant human Bax protein, DsbC & His protein is expressed in E.coli with N-GST&C-CBD-His. It contains the amino acid sequence of 1-192/192.
Applications
ELISA
Endotoxin
Not Tested
Purity
> 95% as determined by SDS- PAGE
Buffer
0.01M TBS (pH7.4)
Storage Conditions
The product should be stored at -70°C or -20°C.
Species
Others
Gene ID URL
581
Available Sizes
Curated Selection
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