BNP peptide/KLH
Product Specifications
Background
Brain natriuretic peptide (BNP), also known as B-type natriuretic peptide, is a hormone secreted by cardiomyocytes in the heart ventricles in response to stretching caused by increased ventricular blood volume. The 32-amino acid polypeptide BNP is secreted attached to a 76–amino acid N-terminal fragment in the prohormone called NT-proBNP (BNPT), which is biologically inactive. Once released, BNP binds to and activates the atrial natriuretic factor receptor NPRA, and to a lesser extent NPRB, in a fashion similar to atrial natriuretic peptide (ANP) but with 10-fold lower affinity. The biological half-life of BNP, however, is twice as long as that of ANP, and that of NT-proBNP is even longer, making these peptides better targets than ANP for diagnostic blood testing.
Gene ID
4879
Swiss Prot
P16860
Expression System
Native protein
Conjugation
Unconjugated
Tag
No tag
Source
Small molecule-conjugated carrier protein
Applications
Others
Endotoxin
Not Tested
Purity
>95% by SDS-PAGE
Buffer
0.01M PBS (pH7.4)
Storage Conditions
Store at -70°C or -20°C. Avoid repeated freeze/thaw cycles.
Gene ID URL
4879
Frequently Asked Questions
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