AMG-7980
Product Specifications
UNSPSC Description
AMG-7980 exhibits high affinity to phosphodiesterase 10A (PDE10A), with a KD of 0.94 nM. AMG-7980 can be used as a tracer of PDE10A, when labeled with radioactive isotope[1].
Target Antigen
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/amg-7980.html
Smiles
CC1=CC(C2=C3C=C(OC)C(OC)=CC3=NN=C2)=CN=C1NC(C)C
Molecular Weight
338.40
References & Citations
[1]Hu E, et al., Rapid identification of a novel small molecule phosphodiesterase 10A (PDE10A) tracer. J Med Chem. 2012 May 24;55(10):4776-87.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-18037/AMG-7980-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-18037/
Clinical Information
No Development Reported
CAS Number
947192-73-6
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