AMG-7980
AMG-7980 exhibits high affinity to phosphodiesterase 10A (PDE10A), with a KD of 0.94 nM. AMG-7980 can be used as a tracer of PDE10A, when labeled with radioactive isotope[1].
Product Specifications
CAS Number
[947192-73-6]
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/amg-7980.html
Smiles
CC1=CC(C2=C3C=C(OC)C(OC)=CC3=NN=C2)=CN=C1NC(C)C
Molecular Formula
C19H22N4O2
Molecular Weight
338.40
References & Citations
[1]Hu E, et al., Rapid identification of a novel small molecule phosphodiesterase 10A (PDE10A) tracer. J Med Chem. 2012 May 24;55 (10) :4776-87.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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