CP-424174
CP-424174 is a reversible inhibitor against IL-1β processing with an IC50 of 210 nM.CP-424174 indirectly inhibits NLRP3[1].
Product Specifications
CAS Number
[210825-31-3]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
NOD-like Receptor (NLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cp-424174.html
Purity
98.03
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=S(C1=CC=CC(C(O)(C)C)=C1)(NC(NC2=C(C=C(C=C2C(C)C)Cl)C(C)C)=O)=O
Molecular Formula
C22H29ClN2O4S
Molecular Weight
452.99
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Alex G Baldwin, et al. Inhibiting the Inflammasome: A Chemical Perspective. J Med Chem
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NLRP3
Available Sizes
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