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Bovine Thyroglobulin

Product Specifications

Background

Bovine thyroglobulin is a large, tetrameric glycoprotein produced in the thyroid gland as a precursor to thyroid hormones. Its large size and absence from plasma under normal conditions makes it very immunogenic and reduces the chance that antibodies to this carrier protein will cross-react with plasma proteins in immunoassays. Haptens may be conjugated to thyroglobulin via accessible secondary amines.Iodine-containing protein that is stored in the thyroid gland. Converted into circulating thyroxines when the thyroid is stimulated by TSH (Thyroid Stimulating Hormone) from the pituitary. Often used as a carrier protein for the production of antibodies. Its advantage as a carrier protein comes from its large number of tyrosine residues that can be used for conjugation using the diazo reaction.

Expression System

Native protein

Conjugation

Unconjugated

Source

Purified native protein

Applications

Others

Endotoxin

Not Tested

Purity

>90% as determined by SDS-PAGE

Buffer

Lyophilized

Storage Conditions

Stored at -70°C or -20°C. Avoid repeated freeze/thaw cycles.

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