NPHS2 Monoclonal Antibody, Biotin Conjugated
Product Specifications
Background
Podocin is an important member of a group of proteins shown to be associated with the slit diaphragm. Podocin belongs to the band 7 stomatin family of lipid raft-associated proteins. It is a hairpin like integral membrane protein with intracellular N and C termini. Podocin is located at the insertion site of the slit membrane, and is thought to act as a scaffold protein required to maintain or regulate the structural integrity of the slit diaphragm. It plays a role in the regulation of glomerular permeability, acting probably as a linker between the plasma membrane and the cytoskeleton.
Synonyms
Nephrosis 2, idiopathic, steroid resistant; NPHS2 gene; PDCN; Podocin; SRN1; PODO_HUMAN
Gene ID
7827
Swiss Prot
Q9NP85
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
NPHS2
Clonality
Monoclonal
Isotype
IgG
Conjugation
Biotin
Applications
WB, IHC-P, IHC-F
Purification
Purified by Protein A.
Concentration
Lot Dependent
Dilution
WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
7827
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
