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Phospho-PKA C alpha/beta/gamma (T197) Recombinant Antibody, HRP Conjugated

Product Specifications

Background

Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis.

Synonyms

CAMP dependent protein kinase catalytic subunit alpha; cAMP dependent protein kinase catalytic subunit beta; cAMP dependent protein kinase catalytic subunit gamma; PKA C alpha; PKA C beta; PKA C gamma; PKACA; PRKACA; PRKACB; PRKACG.

Gene ID

5568

Swiss Prot

P22612, P17612, P22694

Modification Site

Thr197

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

PKA C alpha/beta/gamma

Clonality

Recombinant

Isotype

IgG

Conjugation

HRP

Source

KLH conjugated synthetic peptide derived from human PKA C alpha around the phosphorylation site of T197

Applications

WB, IHC-P, IHC-F

Purification

Purified by Protein A.

Concentration

Lot dependent

Dilution

WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

5568

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