HMGCL Recombinant Antibody, Biotin Conjugated
Product Specifications
Background
Mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S) -3-hydroxy-3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis. Terminal step in leucine catabolism. Ketone bodies (beta-hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism.
Synonyms
HMG CoA lyase; HMGCL; Hydroxymethylglutaricaciduria; MS725.
Gene ID
3155
Swiss Prot
P35914
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Human
Target
HMGCL
Clonality
Recombinant
Isotype
IgG
Conjugation
Biotin
Source
KLH conjugated synthetic peptide derived from human HMGCL
Applications
WB, IHC-P, IHC-F
Purification
Purified by Protein A.
Concentration
Lot dependent
Dilution
WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
3155
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