Phospho-PBK (Thr9) Recombinant Antibody, HRP Conjugated
Product Specifications
Background
Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization and attenuation of G2/M checkpoint during doxorubicin-induced DNA damage.
Synonyms
CT84; MAPKK like protein kinase; Nori3; PBK; PDZ binding kinas; Serine/threonine protein kinase; SPK; TOPK.
Gene ID
55872
Swiss Prot
Q96KB5
Modification Site
Thr9
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human
Target
PBK
Clonality
Recombinant
Isotype
IgG
Conjugation
HRP
Source
KLH conjugated synthetic peptide derived from human PBK around the phosphorylation site of T9
Applications
WB, IHC-P, IHC-F
Purification
Purified by Protein A.
Concentration
Lot dependent
Dilution
WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
55872
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