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Phospho-MDM2 (Ser166) Recombinant Antibody, HRP Conjugated

Product Specifications

Background

E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome.

Synonyms

ACTFS; Hdm2; HDMX; MDM2; MDM2BP; MTBP.

Gene ID

4193

Swiss Prot

Q00987

Modification Site

Ser166

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Human

Target

MDM2

Clonality

Recombinant

Isotype

IgG

Conjugation

HRP

Source

KLH conjugated synthetic peptide derived from human MDM2 around the phosphorylation site of S166

Applications

WB, IHC-P, IHC-F

Purification

Purified by Protein A.

Concentration

Lot dependent

Dilution

WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

4193

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