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Phospho-MDM2 (Ser166) Recombinant Antibody

Product Specifications

Background

E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome.

Synonyms

ACTFS; Hdm2; HDMX; MDM2; MDM2BP; MTBP.

Gene ID

4193

Swiss Prot

Q00987

Modification Site

Ser166

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Human

Target

MDM2

Clonality

Recombinant

Isotype

IgG

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human MDM2 around the phosphorylation site of S166

Applications

WB, IHC-P, IHC-F, IF

Purification

Purified by Protein A.

Concentration

Lot dependent

Dilution

WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500), IF ()

Buffer

0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Modification

Phosphorylation

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

4193

Available Sizes

Frequently Asked Questions

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