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Phospho-EIF4B (Ser406) Recombinant Antibody

Product Specifications

Background

Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.

Synonyms

EIF4B

Gene ID

1975

Swiss Prot

P23588

Modification Site

Ser406

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

EIF4B

Clonality

Recombinant

Isotype

IgG

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human eIF4B around the phosphorylation site of S406

Applications

WB, IHC-P, IHC-F, IF

Purification

Purified by Protein A.

Concentration

Lot dependent

Dilution

WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500), IF ()

Buffer

0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Modification

Phosphorylation

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

1975

Available Sizes

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