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Caspase 5 Recombinant Antibody

Product Specifications

Background

Thiol protease that acts as a mediator of programmed cell death.Initiates pyroptosis, a programmed lytic cell death pathway through cleavage of Gasdermin-D (GSDMD) : cleavage releases the N-terminal gasdermin moiety (Gasdermin-D, N-terminal) that binds to membranes and forms pores, triggering pyroptosis.

Synonyms

CASP5; Apoptosis related cysteine protease; CASP-5; Caspase-5 subunit p10; Protease ICH-3; TY protease.

Gene ID

838

Swiss Prot

P51878

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Human

Target

Caspase 5

Clonality

Recombinant

Isotype

IgG

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human Caspase 5

Applications

WB

Purification

Purified by Protein A.

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Modification

Unmodified

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

838

Available Sizes

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