TMPRSS2 Recombinant Antibody, HRP Conjugated
Product Specifications
Background
Plasma membrane-anchored serine protease that cleaves at arginine residues.Participates in proteolytic cascades of relevance for the normal physiologic function of the prostate. (Microbial infection) Facilitates human coronaviruses SARS-CoV and SARS-CoV-2 infections via two independent mechanisms, proteolytic cleavage of ACE2 receptor which promotes viral uptake, and cleavage of coronavirus spike glycoproteins which activates the glycoprotein for host cell entry.
Synonyms
Epitheliasin; PRSS10; TMPRSS2.
Gene ID
7113
Swiss Prot
O15393
Cellular Locus
Secreted, Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse
Target
TMPRSS2
Clonality
Recombinant
Isotype
IgG
Conjugation
HRP
Source
KLH conjugated synthetic peptide derived from human TMPRSS2
Applications
WB, IHC-P, IHC-F
Purification
Purified by Protein A.
Concentration
Lot dependent
Dilution
WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
7113
Available Sizes
Curated Selection
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