TMPRSS2 Recombinant Antibody
Product Specifications
Background
Plasma membrane-anchored serine protease that cleaves at arginine residues.Participates in proteolytic cascades of relevance for the normal physiologic function of the prostate. (Microbial infection) Facilitates human coronaviruses SARS-CoV and SARS-CoV-2 infections via two independent mechanisms, proteolytic cleavage of ACE2 receptor which promotes viral uptake, and cleavage of coronavirus spike glycoproteins which activates the glycoprotein for host cell entry.
Synonyms
Epitheliasin; PRSS10; TMPRSS2.
Gene ID
7113
Swiss Prot
O15393
Cellular Locus
Secreted, Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse
Target
TMPRSS2
Clonality
Recombinant
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human TMPRSS2
Applications
WB, IHC-P, IHC-F, IF
Purification
Purified by Protein A.
Concentration
Lot dependent
Dilution
WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500), IF ()
Buffer
0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
7113
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