VPS11 Recombinant Antibody, HRP Conjugated
Product Specifications
Background
Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes which are proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion.
Synonyms
END1; hVPS11; PEP5; PP3476; RNF108; vps11.
Gene ID
55823
Swiss Prot
Q9H270
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Human, Mouse
Target
VPS11
Clonality
Recombinant
Isotype
IgG
Conjugation
HRP
Source
KLH conjugated synthetic peptide derived from human VPS11
Applications
WB, IHC-P, IHC-F
Purification
Purified by Protein A.
Concentration
Lot dependent
Dilution
WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
55823
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