SorLA Recombinant Antibody, Biotin Conjugated
Product Specifications
Background
Sorting receptor that directs several proteins to their correct location within the cell (Probable) . Along with AP-1 complex, involved Golgi apparatus - endosome sorting.Sorting receptor for APP, regulating its intracellular trafficking and processing into amyloidogenic-beta peptides. Retains APP in the trans-Golgi network, hence preventing its transit through late endosomes where amyloid beta peptides Abeta40 and Abeta42 are generated.
Synonyms
Gp250; LR11; LRP9; SORL1; SorLA 1; SorLA.
Gene ID
6653
Swiss Prot
Q92673
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
SorLA
Clonality
Recombinant
Isotype
IgG
Conjugation
Biotin
Source
KLH conjugated synthetic peptide derived from human Sortilin related receptor
Applications
WB, IHC-P, IHC-F
Purification
Purified by Protein A.
Concentration
Lot dependent
Dilution
WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
6653
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