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SMN1 Recombinant Antibody, Biotin Conjugated

Product Specifications

Background

The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs.Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP.

Synonyms

SMN2; BCD541; C-BCD541; SMNC; GEMIN1.

Gene ID

6606

Swiss Prot

Q16637

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Human

Target

SMN1

Clonality

Recombinant

Isotype

IgG

Conjugation

Biotin

Source

KLH conjugated synthetic peptide derived from human SMN1

Applications

WB, IHC-P, IHC-F, IP

Purification

Purified by Protein A.

Concentration

Lot dependent

Dilution

WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500), IP (1-2ug)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C for 12 months.

Gene ID URL

6606

Predicted Cross Reactivity

Mouse, Rat

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