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PU.1/Spi1 Recombinant Antibody, HRP Conjugated

Product Specifications

Background

Pioneer transcription factor, which controls hematopoietic cell fate by decompacting stem cell heterochromatin and allowing other transcription factors to enter otherwise inaccessible genomic sites. Once in open chromatin, can directly control gene expression by binding genetic regulatory elements and can also more broadly influence transcription by recruiting transcription factors, such as interferon regulatory factors (IRFs), to otherwise inaccessible genomic regions.

Synonyms

Oncogene spi1; PU.1; SFPI1; SPI 1; SPI A; Spi1.

Gene ID

6688

Swiss Prot

P17947

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human, Mouse

Target

PU.1/Spi1

Clonality

Recombinant

Isotype

IgG

Conjugation

HRP

Source

KLH conjugated synthetic peptide derived from human SPI1

Applications

WB

Purification

Purified by Protein A.

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

6688

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