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ITK Recombinant Antibody

Product Specifications

Background

Interleukin-2 inducible T-cell kinase (Itk, Emt or Tsk) is a member of the non-receptor protein tyrosine kinases. Family members of Itk include Tec, Btk, Rlk and Bmx and are all defined by a common structure: an amino-terminal PH domain, a Tec-homology domain and a SH3 and SH2 domain followed by a carboxy-terminal kinase domain. Tec, Rlk and Itk are expressed in T cells and activated in response to T cell receptor (TCR) engagement.

Synonyms

EMT; Homolog of mouse T cell itk/tsk; IL 2 inducible T cell kinase; Itk; Kinase EMT; LPFS1; LYK; PSCTK2; T cell specific kinase; TSK; Tyrosine protein kinase ITK/TSK.

Gene ID

3702

Swiss Prot

Q08881

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human

Target

ITK

Clonality

Recombinant

Isotype

IgG

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human ITK

Applications

IHC-P, IHC-F, IF, Flow-Cyt

Purification

Purified by Protein A.

Concentration

Lot dependent

Dilution

IHC-P (1:200-400), IHC-F (1:100-500), IF (), Flow-Cyt (1ug/Test)

Buffer

0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Modification

Unmodified

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

3702

Available Sizes

Curated Selection

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