HnRNP K Recombinant Antibody
Product Specifications
Background
Facilitate pre-mRNA processing and transport of mRNA from the nucleus to cytoplasm. hnRNP K contains three unique structural motifs termed KH domains that bind poly (C) DNA and RNA sequences. Intricate architecture enables hnRNP K to facilitate mRNA biosynthesis, transcriptional regulation, and signal transduction. Research studies have shown that cytoplasmic hnRNP K expression is increased in oral squamous cell carcinoma and pancreatic cancer, and may be a potential prognostic factor.
Synonyms
65 kDa phosphoprotein; CSBP; TUNP; HNRNPK; HNRPK; DC-stretch binding protein; hnRNP-K.
Gene ID
3190
Swiss Prot
P61978
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
HnRNP K
Clonality
Recombinant
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human hnRNP K
Applications
WB, IHC-P, IHC-F, IP, IF, ICC/IF
Purification
Purified by Protein A.
Concentration
Lot dependent
Dilution
WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500), IP (1-2ug), IF (), ICC/IF (1:50-100)
Buffer
0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
3190
Available Sizes
Curated Selection
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