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CYP11A1 Recombinant Antibody

Product Specifications

Background

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide. [provided by RefSeq, Jul 2008]

Synonyms

Cholesterol 20 22 desmolase; Cholesterol desmolase; Cholesterol monooxygenase (side chain cleaving) ; Cholesterol side chain cleavage enzyme; Cholesterol side chain cleavage enzyme mitochondrial; Cholesterol side-chain cleavage enzyme; CP11A_HUMAN; CYP11A1; CYPXIA1; Cytochrome P450 11A1; Cytochrome P450 11A1 mitochondrial; Cytochrome P450 family 11 subfamily A polypeptide 1; Cytochrome P450 subfamily XIA; Cytochrome P450 (scc) ; Cytochrome P450C11A1; mitochondrial; P450SCC; Steroid 20 22 lyase.

Gene ID

1583

Swiss Prot

P05108

Cellular Locus

Cytoplasm

Host

Mouse

Cross Reactivity

Human

Target

CYP11A1

Clonality

Recombinant

Isotype

IgG1 κ

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human CYP11A1

Applications

WB, IHC-P, IHC-F, IF, ICC/IF

Purification

Purified by Protein G.

Concentration

1mg/ml

Dilution

WB (WB=1:500-2000), IHC-P (IHC-P=1:50-1:100), IHC-F (ICC=1:50), IF (IF=1:100-500), ICC/IF (1:50-100)

Buffer

0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Modification

Unmodified

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

1583

Predicted Cross Reactivity

Mouse, Rat

Available Sizes

Curated Selection

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