Arg2 Monoclonal Antibody

Arginase I (also designated liver-type arginase), which is expressed almost exclusively in the liver, catalyzes the conversion of arginine to ornithine and urea (1) . The human arginase I gene, which maps to chromosome 6q23, encodes a 322 amino acid protein. Arginase I exists as a homotrimeric protein and contains a binuclear manganese cluster (2-4) . Arginase II catalyzes the same reaction as arginase I, but differs in its tissue specificity and subcellular location (5,6) . Specifically, arginase II localizes to the mitochondria (5,6) . Arginase II is expressed in non-hepatic tissues, with the highest levels of expression in the kidneys, but, unlike arginase I, is not expressed in liver (5,6) . The human arginase II gene, which maps to chromosome 14q24.1, encodes a 354 amino acid protein (3,5-7) . In addition, arginase II contains a putative amino-terminal mitochondrial localization sequence (5,6) .

ARG2 antibody, ARGI2_HUMAN antibody, Arginase II mitochondrial antibody, Arginase type II antibody, Arginase-2 antibody, arginase-2, mitochondrial antibody, Kidney arginase antibody, Kidney type arginase antibody, Kidney-type arginase antibody, L arginine amidinohydrolase antibody, L arginine ureahydrolase antibody, mitochondrial antibody, Non hepatic arginase antibody, Non-hepatic arginase antibody, Nonhepatic arginase antibody, Type II arginase antibody