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Synapsin II Recombinant Antibody

Product Specifications

Background

This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family encodes a neuron-specific phosphoprotein that selectively binds to small synaptic vesicles in the presynaptic nerve terminal. The TIMP4 gene is located within an intron of this gene and is transcribed in the opposite direction. Mutations in this gene may be associated with abnormal presynaptic function and schizophrenia. Alternative splicing of this gene results in two transcripts. [provided by RefSeq, Jul 2008]

Synonyms

SYN 2 antibody, SYN II antibody, SYN IIa antibody, SYN IIb antibody, SYN2 antibody, Synapsin 2 antibody, Synapsin II isoform IIa antibody, Synapsin II isoform IIb antibody, Synapsin2 antibody, SynapsinII antibody, SYNII antibody, SYNIIa antibody, SYNIIb antibody

Gene ID

6854

Swiss Prot

Q92777

Cellular Locus

Cell junction, Synapse

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

Synapsin II

Clonality

Monoclonal

Isotype

IgG

Clone

1G10

Conjugation

Unconjugated

Source

Synthetic Peptide within N-terminal human SYN2.

Applications

WB, IHC-P, IHC-F, IF

Purification

Purified by Protein A.

Concentration

Lot Dependent

Dilution

WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500), IF ()

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C for 12 months.

Gene ID URL

6854

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