Phospho-JAK2 (Y1007+Y1008) Monoclonal Antibody

Product Specifications

Background

This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis. [provided by RefSeq, Jul 2008]

Synonyms

JAK 2 antibody, JAK-2 antibody, JAK2 antibody, JAK2_HUMAN antibody, Janus Activating Kinase 2 antibody, Janus kinase 2 (a protein tyrosine kinase) antibody, Janus kinase 2 antibody, JTK 10 antibody, JTK10 antibody, kinase Jak2 antibody, OTTHUMP00000043260 antibody, THCYT3 antibody, Tyrosine protein kinase JAK2 antibody, Tyrosine-protein kinase JAK2 antibody

Gene ID

3717

Swiss Prot

O60674

Modification Site

Tyr1007+Tyr1008

Cellular Locus

Cytoplasm, Nucleus, Endomembrane system

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

Phospho-JAK2 (Y1007+Y1008)

Clonality

Monoclonal

Isotype

IgG

Clone

3G6

Conjugation

Unconjugated

Source

Synthetic phospho-Peptide corresponding to residues surrounding Tyr1007 and 1008 of human JAK2.

Applications

WB, IHC-P, IF (ICC), IP, IHC

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), IHC-P (1:200-400), IF (ICC) (1:50-200), IP (1-2ug), IHC ()

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C for 12 months.

Gene ID URL

3717

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