ATP2A1 (3G1) Monoclonal Antibody
Product Specifications
Background
Key regulator of striated muscle performance by acting as the major Ca2+ ATPase responsible for the reuptake of cytosolic Ca2+ into the sarcoplasmic reticulum. Catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction.
Synonyms
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1; ATP2A1; SERCA1; SR Ca (2+) -ATPase 1; Calcium pump 1; Calcium-transporting ATPase sarcoplasmic reticulum type fast twitch skeletal muscle isoform; Endoplasmic reticulum class 1/2 Ca (2+) ATPase
Gene ID
487
Swiss Prot
O14983
Cellular Locus
Membrane bound, Endoplasmic reticulum
Host
Rabbit
Cross Reactivity
Human
Target
ATP2A1
Clonality
Monoclonal
Isotype
IgG
Clone
3G1
Conjugation
Unconjugated
Source
Synthetic peptide within human SERCA1 ATPase aa 1-50.
Applications
WB, IHC-P, IF (ICC), IP
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), IHC-P (1:200-400), IF (ICC) (1:50-200), IP (1-2ug)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
487
Curated Selection
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