ACTN2 (7G3) Monoclonal Antibody
Product Specifications
Background
ACTN2 is a member of the alpha-actin binding protein gene family. ACTN2 is primarily expressed in skeletal muscle and functions as a structural component of the sarcomeric Z line. This protein is involved in crosslinking actin containing thin filaments. An allelic polymorphism in this gene results in both coding and non-coding variants; the reference genome represents the coding allele. The non-functional allele of this gene is associated with elite athlete status. ACTN2 is an F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. ACTN2 is a bundling protein.
Synonyms
Alpha-actinin-2; ACTN2; Sarcomeric Alpha Actinin; Alpha-actinin skeletal muscle isoform 2; F-actin cross-linking protein; CMH23; CMD1AA
Gene ID
88
Swiss Prot
P35609
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
ACTN2
Clonality
Monoclonal
Isotype
IgG
Clone
7G3
Conjugation
Unconjugated
Source
Recombinant protein within human ACTN2 aa 1-150.
Applications
WB, IHC-P, IP
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), IHC-P (1:200-400), IP (1-2ug)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
88
Curated Selection
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