MARK3 Recombinant Antibody
Product Specifications
Background
Serine/threonine-protein kinase. Involved in the specific phosphorylation of microtubule-associated proteins for MAP2 and MAP4. Phosphorylates the microtubule-associated protein MAPT/TAU. Phosphorylates CDC25C on 'Ser-216'. Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus. Negatively regulates the Hippo signaling pathway and antagonizes the phosphorylation of LATS1. Cooperates with DLG5 to inhibit the kinase activity of STK3/MST2 toward LATS1.
Synonyms
MAP/microtubule affinity-regulating kinase 3; C-TAK1; cTAK1; Cdc25C-associated protein kinase 1; ELKL motif kinase 2; EMK-2; Protein kinase STK10; Ser/Thr protein kinase PAR-1; Par-1a; Serine/threonine-protein kinase p78; microtubule affinity regulating kinase 3
Gene ID
4140
Swiss Prot
P27448
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse
Target
MARK3
Clonality
Monoclonal
Isotype
IgG
Clone
2F7
Conjugation
Unconjugated
Source
Recombinant protein within human Mark3 aa 600-750.
Applications
WB, FCM, IHC-P, IF (IHC-P), IF (ICC), IP
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), FCM (1:20-100), IHC-P (1:200-400), IF (IHC-P) (1:50-200), IF (ICC) (1:50-200), IP (1-2ug)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
4140
Predicted Cross Reactivity
Rat
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS7168240 Inquire
Rabbit anti-Saccharomyces cerevisiae (strain YJM789)(Baker's yeast) OAF3 Polyclonal Antibody
Ask
View Details