FYB1 (1F10) Monoclonal Antibody
Product Specifications
Background
Acts as an adapter protein of the FYN and LCP2 signaling cascades in T-cells. Modulates the expression of interleukin-2 (IL-2) . Involved in platelet activation. Prevents the degradation of SKAP1 and SKAP2. May play a role in linking T-cell signaling to remodeling of the actin cytoskeleton.
Synonyms
FYN-binding protein 1; Adhesion and degranulation promoting adaptor protein; ADAP; FYB-120/130; p120/p130; FYN-T-binding protein; SLAP-130; SLP-76-associated phosphoprotein; SLAP130; FYB
Gene ID
2533
Swiss Prot
O15117
Cellular Locus
Cytoplasm, Nucleus, Cell junction
Host
Rabbit
Cross Reactivity
Human
Target
FYB1
Clonality
Monoclonal
Isotype
IgG
Clone
1F10
Conjugation
Unconjugated
Source
Recombinant protein within C-terminal human FYB.
Applications
WB, FCM, IHC-P, IHC
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), FCM (1:20-100), IHC-P (1:200-400), IHC ()
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
2533
Curated Selection
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