Aconitase 2 (2F4) Monoclonal Antibody
Product Specifications
Background
Aconitase 2, mitochondrial is a protein that in humans is encoded by the ACO2 gene. The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15 (PRSS15), also known as Lon protease, after oxidative modification.
Synonyms
Aconitate hydratase mitochondrial; Citrate hydro-lyase; Aconitase; ACO2
Gene ID
50
Swiss Prot
Q99798
Cellular Locus
Mitochondrion
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
ACO2
Clonality
Monoclonal
Isotype
IgG
Clone
2F4
Conjugation
Unconjugated
Source
Recombinant protein within human Aconitase 2 aa 1-150.
Applications
WB, IHC-P, IF (IHC-P), IF (ICC), IP
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), IHC-P (1:200-400), IF (IHC-P) (1:50-200), IF (ICC) (1:50-200), IP (1-2ug)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
50
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