Lysyl-tRNA synthetase (1H8) Monoclonal Antibody
Product Specifications
Background
Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. When secreted, acts as a signaling molecule that induces immune response through the activation of monocyte/macrophages. Catalyzes the synthesis of the signaling molecule diadenosine tetraphosphate (Ap4A), and thereby mediates disruption of the complex between HINT1 and MITF and the concomitant activation of MITF transcriptional activity.
Synonyms
Lysine tRNA ligase; Lysyl tRNA synthetase; LysRS; KARS; KIAA0070
Gene ID
3735
Swiss Prot
Q15046
Cellular Locus
Cytoplasm, Nucleus, Secreted, Mitochondrion, Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
KARS
Clonality
Monoclonal
Isotype
IgG
Clone
1H8
Conjugation
Unconjugated
Source
Recombinant protein corresponding to C-terminal human Lysyl tRNA synthetase.
Applications
WB, IHC-P, IP
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), IHC-P (1:200-400), IP (1-2ug)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
3735
More Discoveries
Explore Other Products
Browse additional items from our catalog
GTR15361204 1 Vial
Lentiviral human KRTAP2-1 sgRNA gene knockout kit - Lentiviral human KRTAP2-1 sgRNA gene knockout kit (100)
Sign In for Pricing
View Details 
GTR15096299 1 Vial
Lentiviral human EHF shRNA (UAS) - Lentiviral human EHF shRNA (UAS, RFP) (25)
Sign In for Pricing
View Details 