BANF1 Recombinant Antibody
Product Specifications
Background
Barrier-to-autointegration factor (BANF1) binds non-specifically to double stranded DNA, possibly to play a role in tissue- or cell type-specific gene expression by interacting with different homeodomain transcription factors. BANF1 compresses chromatin structure and interacts with the LEM domain of nuclear proteins to play a crucial role in membrane recruitment and chromatin decondensation during nuclear assembly. Additionally, retroviruses like HIV-1 incorporate BANF1 from host cells into preintegration complexes (PICs) to prevent autointegration of retroviral DNA and thereby promote integration of retroviral DNA into the host chromosome.
Synonyms
Barrier-to-autointegration factor; Breakpoint cluster region protein 1; Barrier-to-autointegration factor N-terminally processed; BANF1; BAF; BCRG1; NGPS; BCRP1
Gene ID
8815
Swiss Prot
O75531
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
BANF1
Clonality
Recombinant
Isotype
IgG
Conjugation
Unconjugated
Source
Full length recombinant protein of human BANF1.
Applications
ELISA, IHC-P, IHC-F, IF, ICC/IF
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (), ICC/IF (1:50-100)
Buffer
0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
8815
Available Sizes
Curated Selection
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