Nectin 2 (3G7) Monoclonal Antibody

Product Specifications

Background

Nectin 2 is a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. Can form trans-heterodimers with PVRL3/nectin-3.

Synonyms

Nectin-2; Herpes virus entry mediator B; Nectin cell adhesion molecule 2; Poliovirus receptor-related protein 2; CD112; Herpesvirus entry mediator B; HveB; NECTIN2, HVEB; PRR2; PVRL2

Gene ID

5819

Swiss Prot

Q92692

Cellular Locus

Extracellular, Cell membrane

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

NECTIN2

Clonality

Monoclonal

Isotype

IgG

Clone

3G7

Conjugation

Unconjugated

Source

Recombinant protein within human Nectin 2 aa 50-250.

Applications

WB, FCM, IHC-P, IF (IHC-P), IF (ICC)

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), FCM (1:20-100), IHC-P (1:200-400), IF (IHC-P) (1:50-200), IF (ICC) (1:50-200)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C for 12 months.

Gene ID URL

5819

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