ADAMTS13 Recombinant Antibody
Product Specifications
Background
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene is the von Willebrand Factor (vWF) -cleaving protease, which is responsible for cleaving at the site of Tyr842-Met843 of the vWF molecule. A deficiency of this enzyme is associated with thrombotic thrombocytopenic purpura. Alternative splicing of this gene generates multiple transcript variants encoding different isoforms.
Synonyms
A disintegrin and metalloproteinase with thrombospondin motifs 13; von Willebrand factor-cleaving protease; ADAM-TS 13; ADAM-TS13; ADAMTS-13; vWF-CP; vWF-cleaving protease; ADAMTS13; C9orf8
Gene ID
11093
Swiss Prot
Q76LX8
Cellular Locus
Secreted
Host
Rabbit
Cross Reactivity
Human
Target
ADAMTS13
Clonality
Recombinant
Isotype
IgG
Conjugation
Unconjugated
Source
Recombinant protein within human ADAMTS13 aa 150-350.
Applications
WB, IHC-P, IHC-F, IF, Flow-Cyt
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500), IF (), Flow-Cyt (1ug/Test)
Buffer
0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
11093
Available Sizes
Curated Selection
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