GOPC (1B8) Monoclonal Antibody
Product Specifications
Background
Plays a role in intracellular protein trafficking and degradation. May regulate CFTR chloride currents and acid-induced ASIC3 currents by modulating cell surface expression of both channels. May also regulate the intracellular trafficking of the ADR1B receptor. May play a role in autophagy. Overexpression results in CFTR intracellular retention and degradation in the lysosomes.
Synonyms
Golgi-associated PDZ and coiled-coil motif-containing protein; CFTR-associated ligand; Fused in glioblastoma; PDZ protein interacting specifically with TC10; PIST; GOPC
Gene ID
57120
Swiss Prot
Q9HD26
Cellular Locus
Cytoplasm, Cell membrane, Golgi apparatus
Host
Rabbit
Cross Reactivity
Human, Mouse
Target
GOPC
Clonality
Monoclonal
Isotype
IgG
Clone
1B8
Conjugation
Unconjugated
Source
Recombinant protein within human PIST aa 1-100.
Applications
WB, FCM, IHC-P, IF (IHC-P), IF (ICC), IP
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), FCM (1:20-100), IHC-P (1:200-400), IF (IHC-P) (1:50-200), IF (ICC) (1:50-200), IP (1-2ug)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
57120
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